CAP Pro Course - Point-of-Care Testing - Prothrombin Time (PT) and INR (2025 & 2026)

Author: Alice Travanty, BS, MT(ASCP)
Reviewer: Joshua J. Cannon, MS, MLS(ASCP)CMSHCM

Continuing Education Credits

Objectives

  • Explain the principles and utilization of the prothrombin time (PT) test and the international normalized ratio (INR).
  • Demonstrate knowledge of the proper procedures for patient identification and sample collection.
  • Follow the correct procedure for performing the POC PT/INR and identify potential sources of error in the testing and demonstrate knowledge of quality practices that will help to minimize error.
  • Discuss the factors affecting the results of a fingerstick INR and the possible side effects of warfarin therapy.

Course Outline

  • Explain the principles and utilization of the prothrombin time (PT) test and the international normalized ratio (INR).
      • Understanding Hemostasis and the Coagulation Cascade
      • Prothrombin Time (PT) and Warfarin Therapy
      • Point-of-Care (POC) Monitoring of Warfarin Therapy
      • Clinical Indications for Warfarin Therapy
      • A new patient comes into the coagulation clinic for testing. He was recently started on warfarin therapy for deep vein thrombosis (DVT). His INR is 1....
      • A new patient comes to the coagulation clinic for a prothrombin time. He is confused when the tech calls the test an INR. He wants to make sure that h...
      • Which of the following terms is defined as "A number provided by the manufacturer of a prothrombin time reagent that denotes how sensitive the reagent...
      • A patient who is being treated for deep vein thrombosis with the oral anticoagulant warfarin has periodic testing to monitor the drug. He is tested at...
      • The prothrombin time (PT) test assesses functional defects. Which of these coagulation pathways is assessed?
  • Demonstrate knowledge of the proper procedures for patient identification and sample collection.
      • Patient Identification and Specimen Labeling
      • Capillary Blood Sample Collection
      • Venipuncture for POC PT/INR Testing
      • Blood Sample Collection for PT/INR Testing by the Laboratory
      • A phlebotomist is having a difficult time obtaining fingerstick blood on his patient who has a POC INR ordered. He sticks the patient once and does no...
      • An outpatient is having blood drawn for an INR which will be tested immediately in the clinic on their portable analyzer in the presence of the patien...
      • Which of the following is an appropriate sample for point-of-care prothrombin time (POC-PT) testing?
      • A 70-year-old male patient presents to the clinic for a POC PT/INR test to evaluate his oral anticoagulant dosage. The POC PT/INR test system that is ...
      • David Lee comes routinely to the hospital's coagulation clinic to have his warfarin therapy monitored. After he checks in, the clinic receptionist esc...
  • Follow the correct procedure for performing the POC PT/INR and identify potential sources of error in the testing and demonstrate knowledge of quality practices that will help to minimize error.
      • Minimizing Error in POC INR Testing
      • Advantages and Limitations of POC PT/INR Testing
      • Quality Management
      • Table: Quality Practices
      • POC INR System Differences
      • A pharmacist adds blood from a fingerstick to the PT/INR test cartridge. The test does not start running. What should she do next?
      • A new shipment of coagulation reagent cartridges arrives in the laboratory. The temperature test strip included with the reagents indicates that the t...
      • In the coagulation clinic, proficiency samples are required to be run for INR/PT. A new employee asks about the requirements for testing the proficien...
      • When gathering all the supplies together to perform a whole blood prothrombin time (PT)/INR, the instrument operator accidentally knocks the analyzer ...
      • A medical laboratory technician (MLT) assists in the coagulation clinic once a week by performing whole blood prothrombin time (PT)/INR testing using ...
  • Discuss the factors affecting the results of a fingerstick INR and the possible side effects of warfarin therapy.
      • Factors Influencing Warfarin Response
      • Correlate the Patient's Condition
      • A patient on anticoagulant therapy indicates on his history update form that he has been recently diagnosed with a malabsorption syndrome. What effect...
      • A patient has had difficulty maintaining a therapeutic prothrombin time level. His physician referred him to an anticoagulant clinic to get the situat...
      • A patient, who regularly comes into the coagulation clinic to monitor his medication, states that he had forgotten to refill his warfarin prescription...
      • A patient is on warfarin therapy and has regular INR testing to monitor the drug. The patient has developed a condition that has resulted in obstructi...
  • References
      • References

Additional Information

Level of Instruction: Intermediate
Intended Audience: This program is designed as an educational and training tool for MLS, MT, and MLT personnel, phlebotomists, medical laboratory science students and interns, pathology residents, and practicing pathologists.
Author Information: Alice Travanty, BS, MT(ASCP), was the Point-of-Care Coordinator for St. Joseph Hospital, Milwaukee, Wisconsin, until her recent retirement from that position. She serves as a technical consultant for Tosa Pediatrics. Alice is the author of article "Connectivity Aids Compliance" in Advance for Administrators of Laboratory Vol 20, Issue 11, page 18. She graduated from Marquette University with a degree in Medical Technology and holds a Point-of-Care Specialist certificate from AACC.
Reviewer Information: Joshua J. Cannon, MS, MLS(ASCP)CMSHCM received his Bachelor of Science and Master of Science in Medical Laboratory Science from Thomas Jefferson University in Philadelphia, PA. He holds Medical Laboratory Scientist and Specialist in Hematology certifications through the ASCP Board of Certification. He was a professor at Thomas Jefferson University for seven years before transitioning into his current role as an Education Developer. His areas of expertise and professional passions include clinical hematology and interprofessional education.

This course is part of the CAP Competency Assessment Hub.

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