Acute Viral Hepatitis Panel

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Authors: Drew Dismukes, MHA, MLS(ASCP) and Kevin F. Foley, PhD, DABCC, MT, SC ;
Reviewer: Alexandru Casapu, MBA, MLS(ASCP)CM, PBTCM

This course provides a review of the acute hepatitis panel. This includes the tests involved, their methodologies, and how their results are interpreted. The course also provides a greater understanding of the Hepatitis A, B, and C viruses, including their respective infection routes, treatment, prognosis, population at risk, and symptoms. At the end of the course, a look at the potential future of hepatitis testing is reviewed.

Continuing Education Credits


  • State reasons and indications for hepatitis testing.
  • List the common causes of acute hepatitis.
  • Discuss testing methods used for the evaluation of hepatitis infection and how results are interpreted.

Course Outline

  • Acute Hepatitis
      • Acute Hepatitis Statistics
      • Acute Hepatitis Panel
    • Patient exhibiting symptoms
      • Purpose of the Acute Hepatitis Panel
      • Symptoms Typical of Acute Hepatitis
      • An acute hepatitis panel assess which of the following infections?
      • Which of the following set of laboratory results is consistent with acute hepatitis?
  • Common causes of acute hepatitis
    • Hepatitis A
      • Hepatitis A Overview
      • Hepatitis A Virus (HAV) Prognosis and Treatment
    • Hepatitis B
      • Hepatitis B Overview
      • Populations at Risk of Hepatitis B Virus (HBV)
      • Acute Hepatitis B Virus (HBV) Prognosis
      • Chronic Hepatitis B Prognosis
      • Hepatitis B Treatment
    • Hepatitis C
      • Hepatitis C Overview
      • Hepatitis C Prognosis
      • Hepatitis C Treatment
    • Other Causes of Hepatitis
      • Which Hepatitis virus is self-limiting, and typically subsides in several weeks?
      • Chronic HBV is most prevalent in which patient population?
      • Other Hepatitis Viruses
  • Acute Viral Hepatitis Panel
      • Overview of the Acute Viral Hepatitis Panel
    • Testing Methods
      • Immunoassay
      • Enzyme Immunoassays
      • Chemiluminescent Immunoassays
    • Hepatitis A IgM Ab
      • Assay and Interpretation
    • Hepatitis B assays
      • Hepatitis B Assays
    • Hep B assay interpretations
      • Interpretation of Hepatitis B assays
      • If both HBsAg and HBcM are positive, what form of hepatitis does the patient have?
      • A reactive HBc IgM assay is selective for acute HBV.
    • Hepatitis C Ab
      • Interpretation
  • Future of Hepatitis Testing
      • Efforts to Lower Hepatitis Rates
      • Future of Hepatitis Testing
      • Future of Hepatitis Testing cont.
      • Conclusion
  • References
      • References

Additional Information

Level of Instruction: Intermediate
Intended Audience: Medical laboratory scientists, medical laboratory technicians, pathology residents, MLS students, and other health care personnel who have an interest in this subject matter. 
Course description: After completion of this course, the student will have a better understanding of acute hepatitis laboratory panels. Laboratory tests, the methodologies employed, and interpretation of results will be covered. The student should also gain a greater understanding of the public health implications of Hepatitis A, B, and C including their prevalence, symptoms, and treatment.
Author information: Drew Dismukes, MHA, MLS(ASCP) has over ten years of experience as a medical laboratory scientist, and charge tech. He currently works at Parkwest Memorial Center. Drew holds a BS in Clinical Lab Science from the University of South Alabama and a MHA from Bellevue University.
Author information: Kevin F. Foley, PhD, DABCC, MT, SC is the director of clinical pathology for the Kaiser Permanente Northwest region. He also teaches clinical chemistry at Oregon Health Sciences University. Dr. Foley earned his PhD in clinical pharmacology and toxicology at East Carolina School of Medicine in North Carolina. He received a PhD in clinical pharmacology and toxicology from Brody School of Medicine, Greenville, NC. He has been working in laboratory medicine for over 15 years, starting his career as a medical technologist. 
Reviewer Information: Alexandru Casapu, MBA, MLS(ASCP)CM, PBTCM, has over 20 years of experience as a medical laboratory scientist, section supervisor, and laboratory manager. He is the former Director of Clinical Laboratory Technology Program at Georgia Piedmont Technical College. He is currently a Program Director at MediaLab, Inc. Alexandru holds BS degrees in Biology and Medical Technology from Clark Atlanta University and a MBA from the University of Georgia.

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This course is part of:
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HAV chart
Hepatitis C Virus